Can You Donate Plasma If You Have Fatty Liver Disease?

Can you donate plasma if you have fatty liver?
Can you donate plasma if you have fatty liver?

A prevalent inquiry among individuals with fatty liver disease is their eligibility for plasma donation. At, we’ve conducted extensive research to address the question: “Can You Donate Plasma If You Have Fatty Liver Disease?” This article provides insights based on current medical guidelines and studies.

Understanding Fatty Liver Disease

Fatty Liver Disease: This condition, encompassing both alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD), is characterized by excess fat accumulation in liver cells. It’s often linked with lifestyle factors like diet and alcohol consumption.

Plasma Donation with Fatty Liver Disease

  1. General Eligibility: The Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee (JPAC) suggests that individuals with non-alcoholic fatty liver disease may be eligible for plasma donation if they are otherwise healthy and managing their condition through diet and lifestyle.
  2. Severe Conditions: Advanced stages of fatty liver disease, such as non-alcoholic steatohepatitis (NASH) or cirrhosis, often disqualify individuals from donating plasma. This is a standard precaution to protect both the donor and the recipient.
  3. Health Assessments: Plasma donation centers conduct health assessments, including liver function tests. Elevated liver enzymes, common in fatty liver disease, might affect donation eligibility.

Insights from

At, our research indicates that while mild fatty liver disease may not preclude plasma donation, advanced stages or complications likely lead to deferral. This aligns with the principle of donor and recipient safety in plasma donation.

Key Considerations

  1. Medical Consultation: It’s essential for individuals with fatty liver disease to seek advice from healthcare providers before considering plasma donation.
  2. Lifestyle Impact: Effective management of fatty liver disease through healthy lifestyle choices can influence plasma donation eligibility.
  3. Ongoing Monitoring: Regular health check-ups and liver function monitoring are crucial, especially for those with fatty liver disease who wish to donate plasma regularly.


In summary, the eligibility to donate plasma with fatty liver disease depends on the condition’s severity and individual health status. Our findings at highlight the importance of personalized health assessments and medical advice in determining plasma donation eligibility for those with fatty liver disease.


  1. JPAC Guidelines on Liver Disease and Blood Donation

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